Seth MacFarlane
Stan Smith / Roger (voice) (22 eps)
Wendy Schaal
Francine Smith (voice) (22 eps)
Rachael MacFarlane
Hayley Smith (voice) (22 eps)
Scott Grimes
Steve Smith (voice) (22 eps)
Dee Bradley Baker
Klaus (voice) (22 eps)
Jeff Fischer
Jeff Fischer (voice) (8 eps)
Patrick Stewart
Avery Bullock (voice) (6 eps)
Richard Kind
Al Tuttle (voice) (6 eps)
Kevin Michael Richardson
Billy (voice) (5 eps)
Nicole Shabtai
Esther Lonstein (voice) (5 eps)
Courtenay Taylor
Coach Cathy (voice) (4 eps)
Khary Payton
Lindsey (voice) (3 eps)
Matthew Mercer
Hank Henderson (voice) (3 eps)
Andy Daly
Memphis Stormfront (voice) (3 eps)
Mike Henry
Jackson (voice) (3 eps)
David Koechner
Dick Reynolds (voice) (3 eps)
Curtis Armstrong
Snot Lonstein (voice) (3 eps)
Jon Daly
Chicago Dave (voice) (2 eps)
Laura Bailey
Piper (voice) (2 eps)
Erin Matthews
Teela (voice) (2 eps)
Yvette Nicole Brown
Hair Salon Customer (voice) (2 eps)
Chris Parnell
Doctor (voice) (1 eps)
Mindy Sterling
Anastasia Kirilenko (voice) (1 eps)
James Adomian
Lorne Mikeys (voice) (1 eps)
Nolan North
College Professor (voice) (1 eps)
Ross Marquand
Mr. Gordon (voice) (1 eps)
Matthew Patrick Davis
Ranch Hand (voice) (1 eps)
Timothy Olyphant
Nowell (voice) (1 eps)
Patton Oswalt
Candy Maker (voice) (1 eps)
J.B. Smoove
Radio Station Security Guard (voice) (1 eps)
Michaela Watkins
Veterinarian (voice) (1 eps)
Carlos Alazraqui
Man on Sidewalk (voice) (1 eps)
Leslie Grossman
Woman on Sidewalk (voice) (1 eps)
Peter MacKenzie
Judge (voice) (1 eps)
Salli Saffioti
Isabella (voice) (1 eps)
Cree Summer
Boat Girl (voice) (1 eps)
Josh Robert Thompson
Robert Stack (voice) (1 eps)
Sarah Adina
HG Member (voice) (1 eps)
Kate Berlant
HG Member (voice) (1 eps)
Tom Kenny
Professsor (voice) (1 eps)
June Diane Raphael
Holly Graham (voice) (1 eps)
Ben Schwartz
Fire Marshall (voice) (1 eps)
Jill Talley
HG Guard (voice) (1 eps)
Casey Wilson
Lindsay (voice) (1 eps)
Paget Brewster
Reporter (voice) (1 eps)
Clancy Brown
Lumberjack (voice) (1 eps)
J. Lee
Partygoer (voice) (1 eps)
Punam Patel
Radika (voice) (1 eps)
Nicole Byer
Jolene (voice) (1 eps)
Chris Diamantopoulos
Fitzwilliam Darcy / Dr. Watson (voice) (1 eps)
Tom Hollander
Mr. Collins / Sherlock Holmes (voice) (1 eps)
Maggie Lowe
Little Girl (voice) (1 eps)
Scottie Pippen
Scottie Pippen (voice) (1 eps)
Laraine Newman
Enuice (voice) (1 eps)
Troy Baker
Christoph Waltz / Jennifer's Husband (voice) (1 eps)
Alex Cuthbertson
Brent Robbins (voice) (1 eps)
Michaela Dietz
New Doctor (voice) (1 eps)
Jak Knight
Stiles (voice) (1 eps)
Natasha Rothwell
Carol (voice) (1 eps)
Kevin Bigley
Perry (voice) (1 eps)
Joe Manganiello
Mike Donkey (voice) (1 eps)
Reggie Lee
Hideki Yoshida (voice) (1 eps)
Robert Wuhl
Robert Wuhl (voice) (1 eps)
Matt McKenna
Buckle (voice) (1 eps)
David Herman
Police Officer (voice) (1 eps)
Chris Pine
Hair Transplant Surgeon (voice) (1 eps)
Daisuke Suzuki
Toshi Yoshida (voice) (1 eps)
Alan Tudyk
Dr. Kalgary (voice) (1 eps)
Daran Norris
Jack Smith (voice) (1 eps)
Swoosie Kurtz
Betty Smith (voice) (1 eps)
Parker Deay
Parker (voice) (1 eps)
Josh Fadem
Tom (voice) (1 eps)