Jennifer Garner
Sydney Bristow (22 eps)
Michael Vartan
Michael Vaughn (22 eps)
Victor Garber
Jack Bristow (22 eps)
Ron Rifkin
Arvin Sloane (22 eps)
Carl Lumbly
Marcus Dixon (22 eps)
Kevin Weisman
Marshall Flinkman (22 eps)
Lena Olin
Irina Derevko (22 eps)
Merrin Dungey
Francie Calfo (22 eps)
Bradley Cooper
Will Tippin (22 eps)
David Anders
Julian Sark (22 eps)
Terry O'Quinn
Kendall (16 eps)
Patricia Wettig
Judy Barnett (4 eps)
James Lesure
Craig Blair (3 eps)
Faye Dunaway
Ariana Kane (3 eps)
Amy Irving
Emily Sloane (2 eps)
Jonathan Banks
Frederick Brandon (2 eps)
Joseph Ruskin
Alain Christophe (2 eps)
Amanda Foreman
Carrie Bowman (2 eps)
Ric Young
Zhang Lee (2 eps)
Rutger Hauer
Anthony Geiger (1 eps)
Christian Slater
Neil Caplan (1 eps)
Richard Lewis
Mitchell Yaeger (1 eps)
Tracy Middendorf
Elsa Caplan (1 eps)
Chris Ellis
Agent Chapman (1 eps)
Mark Humphrey
SD-6 Technician (1 eps)
Ron Yuan
Haz Mat Guy (uncredited) (1 eps)
Danny Trejo
Emilio Vargas (1 eps)
Ethan Hawke
James Lennox (1 eps)
Jim Hanna
Claus Richter (1 eps)
Robert Joy
Hans Jürgens (1 eps)
Pasha D. Lychnikoff
Zoran Sokolov (1 eps)
Derek de Lint
Gerard Cuvee (1 eps)
Stephen Davies
Sark Associate (1 eps)
Chris Harrison
Reporter (1 eps)
Marisol Nichols
Rebecca Martinez (1 eps)
Olivia d'Abo
Emma Wallace (1 eps)
Iqbal Theba
General Arshad (1 eps)
Roger Lim
Taiwanese Gasping Body (1 eps)
David Carradine
Conrad (1 eps)
Clayton Landey
Wilcox (uncredited) (1 eps)
Justin Wade
Drug Store Employee (1 eps)