Oakes Fegley
Ben
Millicent Simmonds
Rose
Julianne Moore
Lillian Mayhew / Rose
Michelle Williams
Elaine
Cory Michael Smith
Walter
James Urbaniak
Dr. Kincaid, Rose's Father
Damian Young
Otto, Museum Guard
Patrick Murney
Workman
Lauren Ridloff
Pearl, The Maid
Anthony Natale
Dr. Gill, Teacher of the Deaf
Carole Addabbo
Miss Conrad at the Museum
Howard Seago
Remy Rubin, Theater Director
Brian Berrebbi
Stage Manager
John P. McGinty
Valentin
Mark A. Keeton
Shopkeeper
Patrick Wiley
Window Dresser
Garrett Zuercher
Officer Engel
Jared Johnston
Officer Murtha
Murphy Guyer
Security Chief
Ekaterina Samsonov
Hannah
Sawyer Niehaus
Blessing
Lilianne Rojek
Florence
Michael W. Gaines
Butler
Jaden Michael
Jamie
Tom Noonan
Walter
Morgan Turner
Janet
Amy Hargreaves
Aunt Jenny
Sawyer Nunes
Robbie
Raul Torres
Jamie's Father
Mandela Bellamy
Woman on Bus
Jim Lavin
ER Doctor
Colleen Cosgrove
ER Nurse
Hays Wellford
Greg Coons at the Bus Stop
Asa Liebmann
Thief
John Boyd
Danny
Oladamolami Adisa
Signing Hands
Mylo Barrett
Signing Hands
Robinho Cruz
Signing Hands
Vanessa DeLeon
Signing Hands
Jordana Lurman
Signing Hands
Tom Waters
1970's Business Man (uncredited)
Connor Moeller
Museum Boy (uncredited)
Mackenzie Grace Castle
Museum Girl (uncredited)
Derek Chadwick
Liam (uncredited)
Logan Taylor
Promenade Child / Museum Child (uncredited)