Will Smith
Capt. James West
Kevin Kline
U.S. Marshal Artemus Gordon / President Grant
Kenneth Branagh
Dr. Arliss Loveless
Salma Hayek Pinault
Rita Escobar
M. Emmet Walsh
Coleman
Ted Levine
General 'Bloodbath' McGrath
Frederique van der Wal
Amazonia
Musetta Vander
Munitia
Sofia Eng
Miss Lippenrieder
Garcelle Beauvais
Belle
Bai Ling
Miss East
Rodney A. Grant
Hudson
E.J. Callahan
Mr. Pinkerton
Debra Christofferson
Dora Look-Alike
Buck Taylor
Cross-Eyed Reb
James Lashly
Reb #1
Dean Rader Duval
Reb #2
Jerry Wills
Other Reb
Mike H. McGaughy
Big reb
Christian Aubert
French Dignitary
Orestes Matacena
Spanish Dignitary
Ian Abercrombie
British Dignitary
Ismael 'East' Carlo
Mexican Dignitary
Bob Rumnock
White House Aide
Gary Carlos Cervantes
Dr. Guillermo Escobar
Jerry Potter
George Washington
Mik Scriba
Guard
Michael Sims
Prof. Thaddeus Morton
J.J. Perry
Shovel Guy (uncredited)
Dennis Keiffer
Wrench Guy (uncredited)
Derek Mears
Metal Head (uncredited)