Garry Shandling
Harold Anderson
Annette Bening
Susan Anderson
John Goodman
Roland Jones
Greg Kinnear
Perry Gordon
Ben Kingsley
Graydon
Judy Greer
Rebecca
Danny Zorn
Randy
Harmony Smith
Rita
Richard Jenkins
Don Fisk
Linda Fiorentino
Helen Gordon
Caroline Aaron
Nadine Jones
Janeane Garofalo
Nervous Woman
Octavia Spencer
Baby Nurse
Nora Dunn
Madeline
Cricky Long
Janice
Camryn Manheim
Alison
Ann Cusack
Liz
Jane Lynch
Doreen
Richard Minchenberg
Dr. Weitzman
Drinda Lalumia
Drunken Lady
J.C. MacKenzie
John
Willie Garson
Brett
Marjorie Lovett
Neighbor Woman
Bil Dwyer
Husband
Alexander Lyras
Male AA
Stacey Travis
Woman
Brian Tee
Alien (uncredited)
Sarah Silverman
Woman on plane
Phill Lewis
Other MD
Rick Avery
Airlane Passenger (uncredited)