Hank Azaria
Gargamel
Neil Patrick Harris
Patrick Winslow
Jayma Mays
Grace Winslow
Jonathan Winters
Papa Smurf (voice)
Katy Perry
Smurfette (voice)
Anton Yelchin
Clumsy Smurf (voice)
Sofía Vergara
Odile Anjelou
Tim Gunn
Henri
Frank Welker
Azrael (voice)
Madison McKinley
Model
Meg Phillips
Model
Mahadeo Shivraj
Cabbie
Julie Chang
Newscaster
Mark Doherty
Bluetooth Businessman
Minglie Chen
Young Woman
Sean Kenin
Guy in Plaid Shirt
Victor Pagan
Bum
Adria Baratta
Anjelou Employee
Paula Pizzi
Odile's Mother
Andrew Sellon
Waiter
Julianna Rigoglioso
Little Sister
Daria Rae Figlo
Blonde Sister
Bradley Gosnell
Toy Salesperson
Heidi Armbruster
Toy Store Parent
Finnerty Steeves
Toy Store Parent
John Speredakos
Parent with Girls
Skai Jackson
Kicking Girl
Alex Hall
Skateboard Kid
Eric Redgate
Skateboard Kid
Jojo Gonzalez
FAO Custodian
Scott Dillin
Cop
Sean Ringgold
Inmate Bubba
Mario D'Leon
Bubba's Inmate Friend
Liz Smith
Party Guest
Tom Colicchio
Party Guest
Michael Musto
Party Guest
Joan Rivers
Party Guest
Olivia Palermo
Party Guest
Julia Enescu
Party Guest
Lauren Waggoner
Party Guest
Mr. Krinkle
Azrael
Alan Cumming
Gutsy Smurf (voice)
Fred Armisen
Brainy Smurf (voice)
George Lopez
Grouchy Smurf (voice)
Kenan Thompson
Greedy Smurf (voice)
Jeff Foxworthy
Handy Smurf (voice)
John Oliver
Vanity Smurf (voice)
Wolfgang Puck
Chef Smurf (voice)
Gary Basaraba
Hefty Smurf (voice)
Paul Reubens
Jokey Smurf (voice)
B.J. Novak
Baker Smurf (voice)
Tom Kane
Narrator Smurf (voice)
John Kassir
Crazy Smurf (Voice)
Joel McCrary
Farmer Smurf (voice)
Mary McGloin
Mother of Girl in Store (uncredited)