Jacob Tremblay
Arnold J. Voorhees
Brian Doyle-Murray
Grandpa Hank
Will Forte
Dr. James Hamilton
Jenny Slate
Suzie Kate Everett
Andy Kindler
Red
Jack Black
Steve
Ike Barinholtz
Hunter
Nick Kroll
Antonie Dodson
Jadon Sand
Finn
Todd Hansen
News Anchor
Brad Abrell
Arnold McFarley
Keith L. Williams
Nolan Hill
Brady Noon
Lloyd Wright
Will Ferrell
The Man Upstairs
Maya Rudolph
Mom
Ralph Fiennes
Carl Perkins
Ron Funches
Mr. Brown
Will Arnett
Andrew Brown
Alec Baldwin
Garrett Solomon
Kenan Thompson
Kenan Connor
Kel Mitchell
Kel Connor
Michael Peña
Sheriff
Doug Nicholas
Policeman
Bill Hader
Joshua Klein
Tom Holland
Spider-Man / Peter Parker
Ken Jeong
Vincent Lee Jones
Jason Ian Drucker
Greg Heffley
Owen Asztalos
Rowley Jefferson
Charlie Wright
Rodrick Heffley
Tom Everett Scott
Frank Heffley
Alicia Silverstone
Susan Heffley
Dylan Walters
Manny Heffley
Wyatt Walters
Manny Heffley
Gavin Lewis
Fregley Jones
Mckenna Grace
Holly Hills
Qayam Devji
Chirag Gupta
Sofia Rosinsky
Patty Farrell
Alan Howard
Sauron
Whoopi Goldberg
Mrs. Brown
Nick Offerman
Adolf Hitler
Elise Vargas
Stella Radner
Zoey Vargas
Stella Radner
Dolph Lundgren
Brenda / He-Man
Tiffany Haddish
Jessica / She-Ra
Ben Affleck
Batman / Bruce Wayne
Billy Eichner
Chet
Eddie Izzard
Chad
Barack Obama
Barack Obama
Joe Biden
President Joe Biden
Donald Trump
Donald Trump
Patton Oswalt
Bob Flynn-Hansen
Kaan Guldur
Jake
Jackie Chan
Mr. Liu
Joaquin Phoenix
Arthur Fleck
Liam Neeson
Bradley Nelson
Winona Ryder
Toni Nelson
Dante Pereira-Olson
Teen Driver
John Mulaney
Johnny Osborne / Alien (voice)
Andy Samberg
Kenny Blomberg / Alien #2 (voice)
Jorma Taccone
Hazmat
Akiva Schaffer
Nathaniel Kaufman
Dave Franco
Justin Shapiro
Khary Payton
Theodore
Nicolette Pierini
Baby / Baby #2
Sophie Fatu
Baby #3
Michael Cera
Scott Pilgrim
Nicholas Briggs
Daleks (voice)
Luke Wilson
Uncle Tom
Noah Schnapp
Kyle O'Brien / Nicky Wood
Ian McKellen
Hunter George
Patrick Stewart
Spencer Brooks