Humphrey Bogart
Samuel Spade
Mary Astor
Brigid O'Shaughnessy
Gladys George
Iva Archer
Peter Lorre
Joel Cairo
Barton MacLane
Lt. of Detectives Dundy
Lee Patrick
Effie Perine
Sydney Greenstreet
Kasper Gutman
Ward Bond
Det. Tom Polhaus
Jerome Cowan
Miles Archer
Elisha Cook Jr.
Wilmer Cook
James Burke
Luke
Murray Alper
Frank Richman
John Hamilton
District Attorney Bryan
Charles Drake
Reporter (uncredited)
Chester Gan
Bit Part (uncredited)
Creighton Hale
Stenographer (uncredited)
Robert Homans
Policeman (uncredited)
William Hopper
Reporter (uncredited)
Walter Huston
Captain Jacoby (uncredited)
Hank Mann
Reporter (uncredited)
Jack Mower
Announcer (uncredited)
Emory Parnell
Ship's Mate (uncredited)