Dudley Moore
Doctor Watson / Mr. Spiggot / Mrs. Ada Holmes / Piano Player
Peter Cook
Sherlock Holmes
Denholm Elliott
Stapleton
Joan Greenwood
Beryl Stapleton
Hugh Griffith
Frankland
Irene Handl
Mrs. Barrymore
Terry-Thomas
Dr. Mortimer
Max Wall
Arthur Barrymore
Kenneth Williams
Sir Henry Baskerville
Roy Kinnear
Selden the Axe Murderer
Dana Gillespie
Mary Frankland
Lucy Griffiths
Iris
Prunella Scales
Glynis
Jessie Matthews
Mrs. Tinsdale
Spike Milligan
Policeman
Penelope Keith
Massage Receptionist
Anna Wing
Sausage and Mash Lady
Vivien Neves
Nun
Josephine Tewson
Nun
Rita Webb
Elder Masseuse
Henry Woolf
Shopkeeper
Jacquie Stevens
Nun