Sandra Bullock
Sarah Ashburn
Melissa McCarthy
Shannon Mullins
Demián Bichir
Hale
Marlon Wayans
Levy
Michael Rapaport
Jason Mullins
Jane Curtin
Mrs. Mullins
Spoken Reasons
Rojas
Dan Bakkedahl
Craig
Taran Killam
Adam
Michael McDonald
Julian
Thomas F. Wilson
Captain Woods
Peter Weireter
SWAT Team Leader
John Ross Bowie
NY Agent
William Xifaras
Tough Guy #1
Cary 'Big Shug' Guy
Tough Guy #2
Erica Derrickson
Prostitute
Tony Hale
John
Deirdre Horgan
Police Dispatch (voice)
William Ambrose Kennedy
Desk Sergeant
Tony V.
Precinct Officer
Amanda Good Hennessey
Woman with Kid
Patty Ross
Drunk Woman
Kaitlin Olson
Tatiana
Ellen Becker Gray
Tatiana's Mother
Andy Buckley
Robin
Don Orsillo
Baseball Announcer
Adam Ray
LeSoire
Chris Gethard
Chris Gethard
Dane Aska
Club Ekko Bartender
Joey McIntyre
Peter Mullins
Michael Tucci
Mr. Mullins
Bill Burr
Mark Mullins
Nate Corddry
Michael Mullins
Jessica Chaffin
Gina
Jamie Denbo
Beth
Miriam Tolan
Pathologist
Alexis Garcia
Drug Dealer in Paint Factory
Raw Leiba
Paint Factory Henchman
Ben Falcone
Blue Collar Man
Joe Stapleton
O'Flanagan's Bartender
Steve Bannos
Wayne
Fletcher McTaggart
Choking Man
Zach Woods
Paramedic
Joe Garland
Boston Agent
Thomas B. Devlin
Boston Agent
Benjamin Evett
Boston Agent
Elliot Santiago
Dealer
Mitch Silpa
Dealer
Luis Da Silva Jr.
Dealer
Steve Grodewald
Dealer
Katie Dippold
ER Nurse
Kelby Turner Akin
Orderly
Lance Norris
Scruffy Bar Patron
Paul Feig
Doctor (uncredited)
John Franchi
Bar Patron (uncredited)
Colleen Kelly
Detective (uncredited)