Grey DeLisle
Mandy (voice)
Ben Diskin
Numbuh 1 / Numbuh 2 / Delightful Children F.D.T.L. (voice)
Lauren Tom
Numbuh 3 (voice)
Dee Bradley Baker
Numbuh 4 / Delightful Children F.D.T.L. (voice)
Cree Summer
Numbuh 5 / Delightful Children F.D.T.L. (voice)
Richard Steven Horvitz
Billy / Harold (voice)
Greg Eagles
Grim (voice)
Matt Levin
Numbuh 60 (voice)
Tony Sampson
Eddy (voice)
C.H. Greenblatt
Fred Fredburger (voice)
Rachael MacFarlane
Mindy / Numbuh 362 (voice)
Vanessa Marshall
Irwin (voice)
Dave Wittenberg
Numbuh 74.239 (voice)
Matt Hill
Ed (voice) (uncredited)
Sam Vincent
Edd (voice) (uncredited)