Ed Helms
Hogan 'Hoagie' Malloy
Jon Hamm
Bob Callahan
Jeremy Renner
Jerry Pierce
Jake Johnson
Randy 'Chilli' Cilliano
Hannibal Buress
Kevin Sable
Annabelle Wallis
Rebecca Crosby
Isla Fisher
Anna Malloy
Rashida Jones
Cheryl Deakins
Leslie Bibb
Susan Rollins
Maxwell Ross
Teen Jerry
Brayden Benson
Young Jerry
Jaren Lewison
Teen Hoagie
Braxton Bjerken
Young Hoagie
Kevin Tyler Moody
Teen Randy
Tyler Crumley
Young Randy
Elijah Marcano
Teen Bob
Braxton Alexander
Young Bob
Xavion Shelton
Teen Kevin
Legend Williams
Young Kevin
Kella Raines
Teen Cheryl
Th'Yana Star
Young Cheryl
Steve Berg
Louis
Nora Dunn
Linda Malloy
Brian Dennehy
Mr. Cilliano
Thomas Middleditch
Dave
Lil Rel Howery
Reggie
Sebastian Maniscalco
Pastor
Indiana Sifuentes
Mexican Jerry
Trayce Malachi
Young Boy in Mall
Jock McKissic
Marvin
Al Mitchell
AA Member
Kate Kneeland
Wedding Caterer
Vince Pisani
Wedding Planner
Kurt Yue
Doctor Yuen
Jim Esposito
Martin - Neighbor
Loren Lott
Sable's Girlfriend
Andrew Tran
Boy Attacker
Carrie Brownstein
Therapist (uncredited)
Courtney Brown
Nurse (uncredited)
Melissa LeEllen
Mall Patron (uncredited)
Donald K. Overstreet
Bar Patron (uncredited)
Grace Pippas
Student (uncredited)
Tatum Price
First Class Passenger (uncredited)
Leslie Sides
Freedom Atlantic Employee (uncredited)
Joey Thurmond
Wedding Guest (uncredited)