Molly Shannon
Mary Katherine Gallagher
Will Ferrell
Sky Corrigan / Jesus
Elaine Hendrix
Evian
Harland Williams
Slater
Mark McKinney
Father Ritley
Glynis Johns
Grandma
Jason Blicker
Howard
Gerry Bamman
Father John
Emmy Laybourne
Helen
Jennifer Irwin
Maria
Rob Stefaniuk
Thomas
Natalie Radford
Autum
Karyn Dwyer
Summer
Tom Green
Dylan
Chuck Campbell
Owen
Jack Newman
Mr. Feinstein
Donna Hanover
Mrs. Corrigan
Dan Redican
Freaky Freddy
Joan Massiah
Crucifix Nun
Jean Howell
Moira McDaniels
Frank Scott
George
Mallory Margel
Little Mary
Deirdre McCloskey
Rosemary Gallagher
David Warrack
Father David
Aidan Kelly
Thornton Gallagher
Jane Moffat
Sister Eileen
Tracy Wright
Sister Anne
Robert Clark
Little Boy Slater
Rick Campanelli
Reporter
Ariel Manson-Wagner
Reporter
Boyd Banks
Weatherman
Sal Scozzari
Special Ed Kid
Christina Gordon
Special Ed Kid
Susie Dias
Special Ed Kid
David Meinke
Special Ed Kid
Tina Campbell
Cheerleader
Christine Nowland
Cheerleader
Carole Mackereth
Cheerleader
Michael McCloskey
Shamus O'Shea
Blake Brooker
Man with Cake
Joanna Bennett
Student (uncredited)
Gabriel Burrafato
Todd (uncredited)
Phil Crowley
Etiquette Record (voice) (uncredited)
Spencer Humm
Choral Singer (uncredited)
Fraser McGregor
Bike Boy (uncredited)
April Morgan
Dancer (uncredited)
Jonathan Gabriel Robbins
Tom, Whose Dad Is Dead (uncredited)
Jason Sehorn
Man in Pink Tutu (uncredited)