Meryl Streep
Karen Silkwood
Kurt Russell
Drew Stephens
Cher
Dolly Pelliker
Craig T. Nelson
Winston
Fred Ward
Morgan
Diana Scarwid
Angela
Ron Silver
Paul Stone
Charles Hallahan
Earl Lapin
Josef Sommer
Max Richter
Sudie Bond
Thelma Rice
Henderson Forsythe
Quincy Bissell
E. Katherine Kerr
Gilda Schultz
Bruce McGill
Mace Hurley
David Strathairn
Wesley
J. C. Quinn
Curtis Schultz
Kent Broadhurst
Carl
Richard Hamilton
Georgie
Les Lannom
Jimmy
M. Emmet Walsh
Walt Yarborough
Graham Jarvis
Doctor at Union Meeting
James Rebhorn
Los Alamos Doctor
Bill Cobbs
Man in Lunchroom
Ray Baker
Pete Dawson
Will Patton
Joe
Tom Stovall
3rd Los Alamos Doctor
Drew Stephens
Waiter (uncredited)
Tess Harper
Linda Dawson
Anthony Heald
2nd Doctor at Union Meeting
Gary Grubbs
Randy Fox