Frank Welker
Scooby-Doo / Fred Jones (voice)
Grey DeLisle
Daphne Blake / Wonder Woman (voice)
Matthew Lillard
Shaggy Rogers (voice)
Kate Micucci
Velma Dinkley (voice)
P.J. Byrne
J.B. (voice)
Victoria Grace
Mercy (voice)
Charles Halford
Lex Luthor (voice)
Nolan North
Computer / Joker / Superman (voice)
Tara Strong
Helen / Lois Lane / Harley Quinn (voice)
Fred Tatasciore
Solomon Grundy / Perry White (voice)
James Arnold Taylor
Jimmy Olsen / Rex Ruthor (voice)
Niccole Thurman
Mayor Flemming (voice)
Sam Vincent
Krypto (voice)
Brian Drummond
Streaky (voice)
Scott McNeil
Ace (voice)