Billy Bob Thornton
Dr. P
Jon Heder
Roger
Jacinda Barrett
Amanda
Sarah Silverman
Becky
Michael Clarke Duncan
Lesher
David Cross
Ian
Horatio Sanz
Diego
Matt Walsh
Walsh
Todd Louiso
Eli
Ben Stiller
Lonnie
Luis Guzmán
Sergeant Moorehead
Dan Fogler
Zack
DeRay Davis
Bee Bee
Jon Glaser
Ernie
Paul Scheer
Little Pete
Joanne Baron
Lois
Omar J. Dorsey
Lawrence
Marcella Lowery
Mrs. Washington
Leonard Earl Howze
Classmate
Jim Parsons
Classmate
Aziz Ansari
Classmate
Remy K. Selma
Classmate
Andy Daly
Classmate
Bob Stephenson
Classmate
Jack Kehler
Classmate
Noel Gugliemi
Subway Guy
Daniel Venegas
Subway Guy
Jessica Stroup
Eli's Wife
Lizz Carter
Flight Attendant
Steve Monroe
Flight Attendant
Malika
Margaret (uncredited)
Khadijah Haqq McCray
Mindy (uncredited)
Nicole Randall Johnson
Shanice (uncredited)
Che Landon
Waitress (uncredited)
Chris Rubio
Airplane Passenger (uncredited)
Bernadette Birkett
Woman (uncredited)