Milla Jovovich
Alice
Wentworth Miller
Chris Redfield
Ali Larter
Claire Redfield
Kim Coates
Bennett
Kacey Clarke
Crystal
Shawn Roberts
Albert Wesker
Sergio Peris-Mencheta
Angel
Boris Kodjoe
Luther West
Spencer Locke
K-Mart
Sienna Guillory
Jill Valentine
Norman Yeung
Kim Yong
Ray Olubowale
Axeman
Christopher Kano
Sniper
Tatsuya Goke
Sniper
Fulvio Cecere
Wendell
Nobuya Shimamoto
Technician #1
Denis Akiyama
Captain Hotaka
Kenta William Tomeoki
Technician #2
Peter Kosaka
Duty Officer
Shin Kawai
Umbrella Sergeant
Mika Nakashima
J Pop Girl
Takato Yamashita
Business Man
Hiromi Okuyama
Kogel Girl Undead
Iain Glen
Dr. Isaacs (archive footage)
Bill Blair
Featured Zombie (uncredited)
Emmanuel Buriez
Zombie (uncredited)
Martin Crewes
Chad Kaplan (uncredited)
Jamie Ferenczi
Survivor (uncredited)
Stefen Hayes
Yuri Loginova (uncredited)
Brian Jansen
Zombie (uncredited)
Azmyth Kaminski
Zombie (uncredited)
Devon Richards
Zombie (uncredited)
Jay Yoo
Japanese soldier (uncredited)