Danny DeVito
Frank Menure
Kathy Bates
Agnes Menure
Ron Livingston
Dr. Richard Clayton
Neve Campbell
Ellen Minnola
Beverly D'Angelo
Angela Minnola
Bob Odenkirk
Mitch Clayton
Edward Herrmann
Doug Clayton
Christine Baranski
Arleen Clayton
Martin Mull
Jeffry Morton
Michael McKean
Ken Hyman
M.C. Gainey
Spicer
Star Jones
Holly Davis
Ed Begley Jr.
Mr. Manoire
Debbi Morgan
Mrs. Manoire
Pete Schwaba
Meat Delivery Man
Jimmy Pardo
Angry Driver
Dierdre Holder
Carol
Rose Abdoo
Frustrated Housewife
Terry Cooley
Prison Inmate
Connie Sawyer
Old Lady
Tracey Walter
Toupee Salesman
Sam Rubin
TV Anchorman
Dave Bautista
Wrestler (uncredited)
Jordan Brower
Prisoner (uncredited)
Jon Donahue
Additional voices (uncredited)
Paul Michael Lévesque
Wrestler (uncredited)