Tom Cruise
Ethan Hunt
Philip Seymour Hoffman
Owen Davian
Ving Rhames
Luther Stickell
Billy Crudup
John Musgrave
Michelle Monaghan
Julia Meade
Jonathan Rhys Meyers
Declan Gormley
Keri Russell
Lindsey Farris
Maggie Q
Zhen Lei
Simon Pegg
Benjamin 'Benji' Dunn
Eddie Marsan
Brownway
Laurence Fishburne
Theodore Brassel
Bahar Soomekh
Davian's Translator
Jeff Chase
Davian's Bodyguard
Michael Berry Jr.
Julia's Kidnapper
Carla Gallo
Beth
Bellamy Young
Rachael
Paul Keeley
Ken
Jane Daly
Julia's Mother
Greg Grunberg
Kevin
Sabra Williams
Annie
Rose Rollins
Ellie
Sasha Alexander
Melissa Meade
Tracy Middendorf
Ashley
Aaron Paul
Rick Meade
Kathryn Fiore
Party Goer
Colleen Crozier
Party Goer
Sean O'Bryan
Party Goer
Bruce French
Minister
Ellen Bry
Lindsey's Mother
Patrick Pankhurst
Lindsey's Father
Tony Guma
Jim
James Shanklin
Hospital Chaplain
Anne Betancourt
Nurse Sally
Antonietta De Lorenzo
Roadblock Driver
Andrea Sartoretti
Roadblock Driver
Antonio Del Prete
Vatican Video Room Guard
Francesco De Vito
Greeting Priest
Giorgio Marchesi
Vatican Gate Guard
Niccolò Senni
Vatican Gate Guard
Paolo Bonacelli
Monsignore
David Waters
IMF Officer
Michael G. Kehoe
Hospital Employee
Timothy Omundson
IMF Agent
José Zúñiga
IMF Agent Pete
William Francis McGuire
IMF Head of Security
Michelle Arthur
Airline Worker
Barney Cheng
Janitor
George Cheung
Shanghai Game Player (uncredited)
Brandon Molale
Torturer (uncredited)
Simon Rhee
Chinese Guard at Hengshan Lu Building (uncredited)
Marcus Young
Chinese Guard (uncredited)
Jerry Trimble
Davian's Thug (uncredited)
Alex Kurtzman
Party Guest (uncredited)
Roberto Orci
Party Guest (uncredited)