Nagarjuna Akkineni
Nageswar Rao / Seetharamudu / Bittu
Nageshwara Rao Akkineni
Chaitanya
Naga Chaitanya Akkineni
Nagarjuna / Radha Mohan
Shriya Saran
Rama Lakshmi / Anjali
Samantha Ruth Prabhu
Krishna Veni / Priya
Brahmanandam
Girish Karnad
Ali Basha
Leonardo DiCaprio
Posani Krishna Murali
Inspector Dharma
Jayaprakash Reddy
Home Minister J.P.
Shankar Melkote
Yashwanth Rayudu
Saranya Ponvannan
Seetharamudu's Mother
Satya Krishnan
Lecturer
Tejaswi Madivada
Divya
M. S. Narayana
Father Francis
Duvvasi Mohan
Home Minister's Assistant
Gundu Sudarshan
Marriage Broker
Saptagiri
Nagarjuna's Friend
Krishnudu
Doctor
Srinivasa Reddy
Car Broker
Chalapathi Rao
Merchant
Amitabh Bachchan
Pratap (Special Appearance)
Amala Akkineni
Dance Teacher (Special Appearance)
Akhil Akkineni
Akhil (Special Appearance)
Neetu Chandra
Air Hostess (Special Appearance)
Raashii Khanna
Prema (Special Appearance)
Lavanya Tripathi
Radha Mohan's Friend (Special Appearance)