Jean Dujardin
Lucky Luke
Melvil Poupaud
Jesse James
Sylvie Testud
Calamity Jane
Alexandra Lamy
Belle
Michaël Youn
Billy The Kid
Daniel Prévost
Pat Poker
Chloé Jouannet
Eleanor
Jean-François Balmer
Le gouverneur
André Oumansky
President
Gabriel Corrado
Luke's Father
Pompeyo Audivert
Undertaker
Atilio Pozzobón
Barman
Alberto Laiseca
Dick Digger
Mathias Sandor
Young Luke
Carolina Presno
Luke's Mother
Carlos Kaspar
Hank
Mirta Wons
Mrs. Flimsey
Jorge Noya
Mr. Flimsey
Claudio Weppler
Phil Defer
Horacio Marassi
Colonel Mc Straggle
Daniel Campomenosi
Dr. Doxey
Kazuomi Takagi
Ming Li Fu
Luciano Cáceres
Henchman
Joaquín Berthold
Henchman
Martín Kohan
Henchman
Óscar Kramer
Politician
Daniela Catz
Saloon Girl
Bruno Salomone
Jolly Jumper (voice)