Diane Keaton
Charlotte Cooper
John Goodman
Sam Cooper
Ed Helms
Hank Cooper
Amanda Seyfried
Ruby
Alan Arkin
Bucky Newport
Steve Martin
Rags (voice)
Olivia Wilde
Eleanor Cooper
Marisa Tomei
Emma Newport
Jake Lacy
Joe Bailey
June Squibb
Aunt Fishy
Alex Borstein
Angie Cooper
Anthony Mackie
Officer Percy Williams
Timothée Chalamet
Charlie Cooper
Blake Baumgartner
Madison Cooper
Maxwell Simkins
Bo Cooper
Dan Amboyer
Jake
Jon Tenney
Dr. Morrissey
Molly Gordon
Lauren Hesselberg
Dorothy Silver
Mrs. Pinkins
Larry McKay
Bob
Sylvia Kauders
Sara
Krista Marie Yu
Lily
Keenan Jolliff
Brady
Kristin Slaysman
Effie Newport
Michael R. Wilson
Young Sam
Elisabeth Evans
Young Charlotte
Quinn McColgan
Young Charlotte (12-14 Yrs)
Sean McGee
Young Bucky
Rory Wilson
Young Emma
Michelle Veintimilla
Kendra
Joe Fishel
Dog Owner
Lev Pakman
Schnozzle Whitehead