Chloë Sevigny
Lizzie Borden
Kim Dickens
Emma Borden
Kristen Stewart
Bridget "Maggie" Sullivan
Jamey Sheridan
Andrew Borden
Fiona Shaw
Abby Borden
Denis O'Hare
John Morse
Jeff Perry
Andrew Jennings
Jody Matzer
Deputy Fleet
Daniel Wachs
Dr. Bowen
Roscoe Sandlin
Judge Blaisdell
Darin Cooper
Jury Foreman
Don Henderson Baker
Marshall Hilliard
Laura Whyte
Mrs. Brayton
Tom Thon
Professor Wood
Tara Ochs
Susan Gilbert
Jay Huguley
William Moody
Katharine Harrington
Matron
Vivian Majkowski
New Housemaid