Jeff Bridges
Dr. Mark Powell
Kevin Spacey
Prot
Mary McCormack
Rachel Powell
Alfre Woodard
Claudia Villars
Ajay Naidu
Dr. Chakaraborty
Vincent Laresca
Navarro
Kimberly Scott
Joyce Trexler
Conchata Ferrell
Betty McAllister
Saul Williams
Ernie
Peter Gerety
Sal
David Patrick Kelly
Howie
Melanee Murray
Bess
Celia Weston
Mrs. Archer
Brian Howe
Steve Becker
Greg Lewis
Dominic McAllister
John Toles-Bey
Russell
Mary Mara
Abby
Brandon de Paul
Josh - Age 10
Tess McCarthy
Natalie Powell - Age 6
Natasha Dorfhuber
Gabby Powell - Age 9
Aaron Paul
Michael Powell - Age 21
William Lucking
Sheriff
Zofia Borucka
Woman on Train
Curt Clendenin
Hospital Patient (uncredited)
Frank Collison
Screaming Man (uncredited)
Moet Meira
Jennifer (uncredited)
Peter Maloney
Duncan Flynn
Lance E. Nichols
David Patel
Erik LaRay Harvey
Security Guard
Paulo Pascoal
Thief (Uncredited)
Tracy Vilar
Maria