John Wayne
Captain Dooley
Lloyd Nolan
Captain Stutz
Walter Abel
Col. Fuller
James Arness
Mac McMullen
Andy Devine
Willie Moon
Allyn Joslyn
J.H. Handy
Jimmy Lydon
Murray, Dooley's navigator
Harry Carey, Jr.
Ralph Hunt, Moon's co-pilot
Hal Baylor
Stankowski, Dooley's engineer
Sean McClory
Frank Lovatt, Dooley's co-pilot
Wally Cassell
D'Annunzia, Dooley's radioman
Gordon Jones
Walrus
Frank Fenton
Captain Turner
Robert Keys
Major Ditson
Sumner Getchell
Lieutenant Cord
Regis Toomey
Sergeant Harper
Paul Fix
Wally Miller
Jim Dugan
Gidley
George Chandler
Rene
Louis Jean Heydt
Fitch
Bob Steele
Wilson
Darryl Hickman
Swanson
Mike Connors
Gainer
Cass Gidley
Stannish
Herbert Anderson
Breezy
Anthony De Mario
Ogden
Ann Doran
Moon's Wife (uncredited)
Fess Parker
Fitch's Co-Pilot (uncredited)
William A. Wellman
Narrator (voice) (uncredited)
Dawn Bender
Murray's Wife
Carl Switzer
Sonny Hopper