Lea Thompson
Beverly Switzler
Jeffrey Jones
Dr. Walter Jenning
Tim Robbins
Phil Blumburtt
Ed Gale
Howard T. Duck
Holly Robinson Peete
K.C., Cherry Bomb
David Paymer
Larry, Scientist
Paul Guilfoyle
Lieutenant Welker
Richard Edson
Ritchie
Dominique Davalos
Cal, Cherry Bomb
Liz Sagal
Ronette, Cherry Bomb
Chip Zien
Howard T. Duck (voice)
Tommy Swerdlow
Ginger Moss
Miles Chapin
Carter
Richard McGonagle
First Cop
Virginia Capers
Cora Mae, Secretary
Debbie Lee Carrington
Additional Ducks
Miguel Sandoval
Bar Entertainment Supervisor
Sheldon Feldner
Hot Tub Spa Owner
Paul Comi
Dr. Chapin
James Lashly
State Trooper
William Hall
Officer Hanson
John Fleck
Pimples
Nancy Fish
Homeless Bag Lady
Wood Moy
Chef
Kristopher Logan
Punk
Brandon Erickson
*uncredited* Man on bike