Ron Perlman
Hellboy
Selma Blair
Elizabeth 'Liz' Sherman
Doug Jones
Abraham 'Abe' Sapien
John Hurt
Prof. Trevor 'Broom' Bruttenholm
Rupert Evans
John Myers
Jeffrey Tambor
Tom Manning
Ladislav Beran
Karl Ruprecht Kroenen
Bridget Hodson
Ilsa Haupstein
Karel Roden
Grigori Rasputin
Brian Steele
Sammael
Corey Johnson
Agent Clay
Kevin Trainor
Young 'Broom'
Brian Caspe
Agent Lime
James Babson
Agent Moss
Stephen Fisher
Agent Quarry
Garth Cooper
Agent Stone
Angus MacInnes
Sgt. Whitman
Jim Howick
Cpl. Matlin
Mark Taylor
Truck Driver
Daniel Aarsman
Kid
Bettina Ask
Kid
Álvaro Navarro
Kid
Emilio Navarro
Kid
Rory Copus
Kid on Rooftop
Tara Hugo
Doctor Jenkins
Richard Haas
Second Doctor
Andrea Miltner
Doctor Marsh
Jo Eastwood
Down's Patient
Charles Grisham
Museum Guard
Jan Holíček
Museum Guard
Jeremy Zimmermann
Lobby Guard
Monty L. Simons
Orderly
Pavel Cajzl
Sherpa Guide
Andrea Stuart
Girl with Kittens
William Hoyland
General Klaus Werner von Krupt
Millie Wilkie
Young Liz
Bob Sherman
Television Host
Ellen Savaria
Blonde Television Reporter
Petr Sekanina
German Scientist
Aleš Košnar
German Scientist
Justin Svoboda
Young Guy
Winter Ave Zoli
Girlfriend
Santiago Segura
Train Driver
Albert Moy
Train Driver
David Hyde Pierce
Abe Sapien (voice) (uncredited)
Helene Maksoud
Liz Sherman's Mother (uncredited)
Guillermo del Toro
Guy Dressed as Dragon (uncredited)
Mike Mignola
Knight (uncredited)
Miroslav Lhotka
Museum Guard (uncredited)
Michael Lindsay
Security Guard (voice) (uncredited)
Todd Kramer
Radioman (uncredited)