Kiana Madeira
Sarah Fier / Deena Johnson
Ashley Zukerman
Solomon Goode / Nick Goode
Gillian Jacobs
Adult Ziggy / C. Berman
Olivia Scott Welch
Hannah Miller / Samantha 'Sam' Fraser
Benjamin Flores Jr.
Henry Fier / Josh Johnson
Darrell Britt-Gibson
Martin P. Franklin
Sadie Sink
Constance / Christine 'Ziggy' Berman
Emily Rudd
Abigail / Cindy Berman
McCabe Slye
Mad Thomas / Tommy Slater
Julia Rehwald
Lizzie / Kate Schmidt
Fred Hechinger
Isaac / Simon Kalivoda
Jordana Spiro
The Widow / Mary Lane
Jordyn DiNatale
Ruby Lane
Elizabeth Scopel
'Real' Sarah Fier
Randy Havens
George Fier
Matthew Zuk
Elijah Goode / Mayor Will Goode
Michael Chandler
'The Pastor' Cyrus Miller
Lacy Camp
Grace Miller / Mrs. Fraser
Jeremy Ford
Caleb / Peter
Patrick Roper
Union Townsman 1
Robert Bryan Davis
Union Townsman 2
Lynne Ashe
Union Townswoman
Charlene Amoia
Beth Kimball / Rachel Thompson
Mark Ashworth
Jakob Berman
Todd Allen Durkin
The Watchman / Officer Kapinski
Ryan Simpkins
Alice
Noah Bain Garret
Skull Mask
Keil Oakley Zepernick
'Shame Killer' Isaac Milton
Emily Brobst
Billy Barker
Kevin Waterman
'The Milkman' Harry Rooker
Ted Sutherland
Young Nick Goode
Lloyd Pitts
Nightwing Killer
Daniel Thomas May
Officer Kuzio
Meghan Packer
TV Anchor
Nilah Blasingame
Highschool Kid
Rachel Doman
Queen of Air and Darkness Girl
Maya Hawke
Heather Watkins (archive footage) (uncredited)