Seth MacFarlane
Peter Griffin / Brian Griffin / Stewie Griffin / Glenn Quagmire / Tom Tucker / Dr. Elmer Hartman / Captain Seamus / Carter Pewterschmidt / Additional Voices (voice)
Alex Borstein
Lois Griffin (voice)
Seth Green
Chris Griffin (voice)
Mila Kunis
Meg Griffin (voice)
Mike Henry
Cleveland Brown / John Herbert / Consuela / Bruce the Performance Artist (voice)
Drew Barrymore
Jillian Russell (voice)
H. Jon Benjamin
Carl (voice)
David Boreanaz
Aurora Boreanaz
John G. Brennan
Mort Goldman (voice)
Karley Scott Collins
Abby / Little Girl (voice)
Chris Cox
Jerry's Friend (voice)
Carrie Fisher
Angela (voice)
Ralph Garman
Truck Driver / Dan (voice)
J. Lee
Souvenir T-Shirt Owner (voice)
Ron MacFarlane
Narrator
Bruce McGill
Santa Claus (voice)
Will Ryan
Winnie the Pooh (voice)
Chris Sheridan
Gary Busey / Truck Driver / Blind Elf (voice)
Danny Smith
Jerry / Doctor Elf (voice)
Tara Strong
Dan's Wife (voice)
Alec Sulkin
Bellgarde (voice)
Jennifer Tilly
Bonnie Swanson (voice)
John Viener
Tomik / Mall Santa / Eeyore / Robert (voice)
Nana Visitor
Mother (voice)
Patrick Warburton
Joe Swanson (voice)
Adam West
Mayor Adam West (voice)