Michael Douglas
Dr. Nathan Conrad
Sean Bean
Patrick Koster
Brittany Murphy
Elisabeth Burrows
Skye McCole Bartusiak
Jessie Conrad
Guy Torry
Dolen
Jennifer Esposito
Det. Sandra Cassidy
Famke Janssen
Aggie Conrad
Oliver Platt
Dr. Louis Sachs
Shawn Doyle
Russel Maddox
Victor Argo
Sydney Simon
Conrad Goode
Max Dunlevy
Paul Schulze
Jake
Lance Reddick
Arnie
Aidan Devine
Leon Edward Croft
Alex Campbell
Jonathan
Philip DeWilde
Intern
Sam Montesano
Frankie
Arlene Duncan
Aide
Judy Sinclair
Zelda Sinclair
Larry Block
Doorman
David Warshofsky
Ryan
Darren Frost
Janitor
Philip Williams
Large Cop
Louis Vanaria
Cop at Scene
Daniel Kash
Detective Garcia
Lucie Laurier
Vanessa
Isabella Fink
8-Year-Old Elisabeth
Ray Iannicelli
Man at Marina
Colm Magner
Cop #1
Cyrus Farmer
Officer #1
Martin Roach
Transit Cop
Patricia Mauceri
Sofia
Tony Bruno
Radio Host (uncredited)
Paul J.Q. Lee
Man with a Cell Phone (uncredited)
Lorli Villanueva
Chinese Woman (uncredited)