Steve Carell
Gru (voice)
Kristen Wiig
Agent Lucy Wilde (voice)
Benjamin Bratt
Eduardo 'El Macho' Pérez (voice)
Miranda Cosgrove
Margo (voice)
Russell Brand
Dr. Nefario (voice)
Ken Jeong
Floyd Eagle-san (voice)
Steve Coogan
Silas Ramsbottom (voice)
Elsie Fisher
Agnes (voice)
Dana Gaier
Edith (voice)
Moisés Arias
Antonio Pérez (voice)
Nasim Pedrad
Jillian (voice)
Kristen Schaal
Shannon (voice)
Pierre Coffin
Kevin / Bob / Stuart / Additional Minions / Evil Minions (voice)
Chris Renaud
Additional Minions / Evil Minions / Italian Waiter (voice)
Nickolai Stoilov
Arctic Lab Guards (voice)
Vanessa Bayer
Flight Attendant (voice)
Ava Acres
Additional Voices (voice)
Lori Alan
Additional Voices (voice)
Jack Angel
Additional Voices (voice)
Eva Bella
Additional Voices (voice)
Georgia Cook
Additional Voices (voice)
John Cygan
Additional Voices (voice)
Debi Derryberry
Additional Voices (voice)
Jess Harnell
Additional Voices (voice)
Danny Mann
Additional Voices (voice)
Mona Marshall
Additional Voices (voice)
Mickie McGowan
Additional Voices (voice)
Mason McNulty
Additional Voices (voice)
Alec Medlock
Additional Voices (voice)
Laraine Newman
Additional Voices (voice)
Jan Rabson
Additional Voices (voice)
Andre Robinson
Additional Voices (voice)
Katie Silverman
Additional Voices (voice)
Casey Simpson
Additional Voices (voice)
Claira Nicole Titman
Additional Voices (voice)
Jim Ward
Additional Voices (voice)
April Winchell
Additional Voices (voice)
Joe Matthews
Additional Voices (voice)