John Candy
Jack Gable
Mariel Hemingway
Janet Dubois / Louise
Emma Samms
Rachel Hedison / Laura Claybourne
Raymond Burr
Carter Hedison
Dylan Baker
Blake Hedison
Charles Rocket
Ty Hedison
David Rasche
Dr. Paul Kirkwood / Dennis
Andrea Thompson
Nurse Helen Caldwell
Zach Grenier
Mickey
Jerry Orbach
Lou Sherwood
Renée Taylor
Arlene Sherwood
Milt Oberman
Fetterman
Mark Boone Junior
Cable Man
Tony Steedman
Edward
Rita Gomez
Marge
Stephanie Segal
TV Reporter
Mark Zuelke
Chauffeur
Dick Durock
Riley
Anthony G. Schmidt
Mason
Murray Rubin
Manny
Peter Bromilow
Auctioneer
Patrick Bristow
Bellboy
Jason Ross-Azikiwe
Manu
Brooke Ashley
Cheerleader Donna McKenzie
Glenn Dixon
Elderly Man
Paul Tuerpe
Waiter
Fred Morsell
Choking Man
Zack Phifer
Attendant
Susan Isaacs
Marie
Marvin Kaplan
Typewriter Repairman
Elaine Swayneson
Secretary
Jay Della
Ashford Falls Cable Man
Michael Caldwell
Busboy
Bill Wittman
Soap Announcer
John D. Bair
Xerox Delivery Man (uncredited)
Robert M. Bouffard
Office Clerk (uncredited)
Robert David Crane
Bob (uncredited)
Margot Kidder
Woman in Washroom (uncredited)
Tom Mankiewicz
Man on Stretcher (uncredited)
Robert Wagner
Jack Gates (uncredited)