Adrienne Barbeau
Virtual Narrator (voice)
Cody Longo
Agent Jae Novak
Cortney Palm
Agent Toria Boon
Michael Berryman
Crau
Barbara Crampton
Dr. Karen Redmane
Sid Haig
Icicle Killer
Lindsay Hartley
Balthoria
Kane Hodder
Sieg
Lloyd Kaufman
Dr. Chalice
Camille Keaton
Kristi Boon
R.A. Mihailoff
Prison Badass Leader
Bill Moseley
Giger
Bill Oberst Jr.
Satan Creator
Felissa Rose
Dr. Angela Freeman
Tony Todd
The Farmer Asa
Dee Wallace
Dr. Eileen Fletcher
Vernon Wells
Nela
Sean Whalen
Satan
Tiffany Shepis
Doctor Peter
Debbie Rochon
Leatherlace
Brinke Stevens
Doctor Banks
Beverly Randolph
Doctor Tarman
Elissa Dowling
Doctor Rowena
Yan Birch
Doctor Phibes
Larry Zerner
Shelly the Prop Man
Gunnar Hansen
Albert Kenny
Michael Kean
Prisoner
Tony Moran
Death House Inmate
Gabrielle Stone
Linz Haddon
Sarah French
Icicle Killer's Victim (uncredited)
Maxine Wasa
Homeless Girl
Bernhard Forcher
Antichrist
Michael Guarnera
Commander Bradshaw
Steven Chase
Corporal Salerno
Anthony Hoang
Subordinate Soldier
Steve Nappe
Bijhead
Greg Pronko
Rioting Prisoner
Lauren Compton
Dr. Logan Harrison
Dmitri Schuyler-Linch
Bennett's Cast (uncredited)