Ryan Reynolds
Wade Wilson / Deadpool
Morena Baccarin
Vanessa
Ed Skrein
Ajax
T.J. Miller
Weasel
Gina Carano
Angel Dust
Leslie Uggams
Blind Al
Brianna Hildebrand
Negasonic Teenage Warhead
Karan Soni
Dopinder
Jed Rees
Recruiter
Stefan Kapičić
Colossus (voice)
Randal Reeder
Buck
Isaac C. Singleton Jr.
Boothe
Michael Benyaer
Warlord
Style Dayne
Jeremy (Pizza Guy)
Kyle Cassie
Gavin Merchant
Taylor Hickson
Meghan Orlovsky
Ayzee
Teen Girl #1
Naika Toussaint
Teen Girl #2
Justyn Shippelt
Arcade Ticket Taker
Donna Yamamoto
Oncologist
Hugh Scott
David Cunningham
Cindy Piper
Chinatown Merchant
Em Haine
Whisper Girlfriend
Aatash Amir
Whisper Boyfriend
Chad Riley
Pool Hall Goon
Paul Belsito
Fight Club Boss
Darcey Johnson
Garbage Truck Driver
Kyle Rideout
Super Soldier #1
Jason William Day
Super Soldier #2
Stan Lee
Strip Club DJ
Benjamin Wilkinson
No5 Orange Manager
Rachel Sheen
Strip Club Worker
Paul Lazenby
Flight Deck Guard
Rob Hayter
Bob
Andre Tricoteux
On-Set Colossus (uncredited)
Victoria De Mare
Stripper (uncredited)
Heather Ashley Chase
Stripclub Pole Performer (uncredited)
Kayla Adams
Waitress Kelly (uncredited)
Olesia Shewchuk
Guadalajaran Mother (uncredited)
Fabiola Colmenero
Guadalajaran Nurse (uncredited)
Matthew Hoglie
Strip Club Patron (uncredited)