Matthew McConaughey
Ron Woodroof
Jennifer Garner
Eve
Jared Leto
Rayon
Denis O'Hare
Dr. Sevard
Steve Zahn
Tucker
Michael O'Neill
Richard Barkley
Dallas Roberts
David Wayne
Griffin Dunne
Dr. Vass
Kevin Rankin
T.J.
Donna DuPlantier
Nurse Frazin
Deneen Tyler
Denise
J.D. Evermore
Clint
Ian Casselberry
Hispanic Orderly
Noelle Wilcox
Kelly
Bradford Cox
Sunny
Rick Espaillat
Michael
Lawrence Turner
Foreman
Lucius Falick
Freddie
James DuMont
Rayon's Father
Jane McNeill
Francine Suskind
Don Brady
Tucker's Father
Matthew Thompson
Effeminate Man
Tony Bentley
Judge
Sean Boyd
Border Agent
Rachel Wulff
News Anchor
Neeona Neal
Stripper
Scott Takeda
Mr. Yamata
Jonathan Tabler
Rick Ferris
Joji Yoshida
Dr. Hiroshi
Carl Palmer
FDA Customs Agent
Martin Covert
Ian
Craig Borten
Quicksilver Cowboy
Henry Frost
Gay Cowboy
Arthur Smith
Rodeo Announcer
Adam Dunn
Neddie Jay (uncredited)
Juliet Reeves London
Rodeo Girl (uncredited)
Jeanine Hill
Rodeo Girl (uncredited)
Sarah Eilts
Ron's Hooker (uncredited)
Lily Virginia Filson
Dancer (uncredited)
Steffie Grote
The Girl With The Snake Tattoo (uncredited)