Frank Welker
Fred Jones / Scooby-Doo (voice)
Casey Kasem
Shaggy Rogers (voice)
Grey DeLisle
Daphne Blake (voice)
Mindy Cohn
Velma Dinkley (voice)
Kim Mai Guest
Minga (voice)
René Auberjonois
Alphonse LaFleur (voice)
Alfred Molina
Professor Jeffries (voice)
James Sie
Pemba Shepra (voice)
James Hong
The High Lama (voice)
Jeff Bennett
Dell Chillman / Pilot (voice)