Julian Sands
Dr. Nick Cavanaugh
Sherilyn Fenn
Helena
Bill Paxton
Ray O'Malley
Art Garfunkel
Dr. Lawrence Augustine
Betsy Clark
Anne Garrett
Kurtwood Smith
Dr. Alan Harrison
Nicolette Scorsese
Fantasy Lover / Nurse
Meg Register
Marion Cavanaugh
Bryan Smith
Russell
Marla Levine
Patricia
Kim Lentz
Nurse Diane
Lloyd T. Williams
Sam the Clerk
Carl Mazzocone Sr.
Pastor
Erik Shoaff
Uncle Charlie
Lisa Oz
Flower Shop Girl
Ted Manson
Mailman
Adele K. Schaeffer
Flashback Party Woman #1
Amy Levin
Flashback Party Woman #2
Matt Berry
Young Nick Cavanaugh
D. Taylor Loeb
Laura (uncredited)