John Getz
Ray
Frances McDormand
Abby
Dan Hedaya
Julian Marty
M. Emmet Walsh
Loren Visser
Samm-Art Williams
Meurice
Deborah Neumann
Debra
Raquel Gavia
Landlady
Van Brooks
Man from Lubbock
Señor Marco
Mr. Garcia
William Creamer
Old Cracker
Loren Bivens
Strip Bar Exhorter
Bob McAdams
Strip Bar Senator
Shannon Sedwick
Stripper
Nancy Finger
Girl on Overlook
William Preston Robertson
Radio Evangelist (voice)
Holly Hunter
Helene Trend (voice) (uncredited)
Barry Sonnenfeld
Marty's Vomiting (voice) (uncredited)