James Franciscus
Brent
Kim Hunter
Dr. Zira
Charlton Heston
Taylor
Maurice Evans
Dr. Zaius
Linda Harrison
Nova
Paul Richards
Mendez
Victor Buono
Fat Man
James Gregory
Ursus
Jeff Corey
Caspay
Natalie Trundy
Albina
Thomas Gomez
Minister
Don Pedro Colley
Ongaro
David Watson
Cornelius
Tod Andrews
Skipper
Eldon Burke
Gorilla Sgt.
Gregory Sierra
Verger
Lou Wagner
Luicius (archive footage)
Army Archerd
Gorilla (uncredited)
Edward Bach
Picket (uncredited)
James Bacon
Ape (uncredited)
Stan Barrett
Gorilla (uncredited)
Angelina Bauer
Chimp Protestor (uncredited)
Erlynn Mary Botelho
Ape (uncredited)
Maxine Botelho
Chimp Protester (uncredited)
Dick Bullock
Gorilla (uncredited)
Bruce Fleischer
Gorilla (uncredited)
Paul Frees
Ending Voiceover (uncredited) (voice)
Roddy McDowall
Cornelius (archive footage) (uncredited)
Hank Robinson
Bomb Worshipper (uncredited)