Paul Giamatti
Barney Panofsky
Dustin Hoffman
Izzy Panofsky
Rosamund Pike
Miriam Grant-Panofsky
Minnie Driver
The 2nd Mrs. P
Scott Speedman
Boogie
Rachelle Lefevre
Clara 'Chambers' Charnofsky
Bruce Greenwood
Blair
Mark Addy
Detective O'Hearne
Macha Grenon
Solange
Jake Hoffman
Michael Panofsky
Anna Hopkins
Kate Panofsky
Saul Rubinek
Charnofsky
Harvey Atkin
2nd Mrs. P's Father
Linda Sorensen
2nd Mrs. P's Mother
Brittany Drisdelle
Girl at Cafe
Thomas Trabacchi
Leo
Clé Bennett
Cedric
Paul Gross
Constable O'Malley of the North
Maury Chaykin
Wedding Guest
Larry Day
Bartender at Wedding
Mark Camacho
T / U Productions Executive #1
Harry Strandjofski
Dr. Morty
Atom Egoyan
O'Malley Director #1
David Cronenberg
O'Malley Director #2
Ted Kotcheff
Train Conductor
David Pryde
T / U Productions Executive #1
Paula Jean Hixson
Bartender at Grumpy's
Marica Pellegrinelli
The Countess
Domenico Minutoli
Judge at Rome Wedding
Massimo Wertmüller
Rome Doctor
Howard Jerome
Uncle Irv
Sam Stone
Fundraising Target #1
Burney Lieberman
Fundraising Target #2
Morty Bercovitch
Fundraising Target #3
Pauline Little
The 2nd Mrs. P's Housekeeper
Robin Kazdan
Wedding Guest
Len Richman
Rabbi
Sheila Hymans
Rabbi's Wife
Kyle Switzer
Production Assistant
Rebecca Croll
Receptionist #1
Steve Bienstock
NY Restaurant Waiter
Arthur Holden
Notary
Zack Kifell
Young Michael Panofsky
Simone Richler
Young Kate Panofsky
Denys Arcand
Maitre'D at Ritz
Arthur Grosser
Mr. Dalhousie
Pascale Bourbeau
Woman at Cemetery
Ellen David
Massage Parlour Madame
Katia Di Perna
Masseuse
Marina Eva
Leo's Girlfriend
Sandra Lavoie
Barney's One Night Stand
Ivana Shein
Receptionist #2
Mélanie St-Pierre
O'Malley's New Co-Star
Tarah Schwartz
Reporter
Richard J. Lewis
Pathologist
Howard Rosenstein
Cousin Jeff