Max Minghella
Jerome
Sophia Myles
Audrey
John Malkovich
Professor Sandiford
Jim Broadbent
Jimmy
Matt Keeslar
Jonah
Ethan Suplee
Vince
Joel David Moore
Bardo
Nick Swardson
Matthew
Anjelica Huston
Art History Teacher
Adam Scott
Marvin Bushmiller
Jack Ong
Professor Okamura
Scoot McNairy
Army-Jacket
Jeremy Guskin
Eno
Monika Ramnath
Flower
Isaac Laskin
Kiss-Ass
Mike Stanley
Martel Drinker
Brian Turk
Cliffy
Jeanette Brox
Shilo
Finneus Egan
Vegan
Shelly Cole
Filthy-Haired Girl
Jean St. James
Mom
Cristen Coppen
Preppy Girl
Michael Shamus Wiles
Donald Baumgarten
Katherine Moennig
Candace
Ezra Buzzington
Leslie
Lauren Lee Smith
Beat Girl
Travis Walck
Richard Natwick
Paul Collins
Professor David Zipkin
Marshall Bell
Lonny
Chris L. McKenna
Mikey
Marc Vann
Kevin
Roxanne Day
Jonah's Wife - Marie
Roxanne Hart
Mom Platz
Osman Soykut
Dad Platz
Katija Pevec
Cynthia Platz
Edith Jefferson
Doddering Aunt
Michael Lerner
Art Dealer
Jeff LeBeau
Lawyer
Richard Bakalyan
Cranky Guard
Kimi Reichenberg
Suburban Girl
John Bliss
Vince's Grandpa
Charlie Talbert
Vince's Editor
Amy Gross
Vince's Editor's Girlfriend
Alexandra Ryan
Nympho Slut
Bob Golub
Hector
Lauren Bowles
Woman Strangled
Zachary Maurer
Young Jerome
Brendan Walsh
Eugene
Brian Geraghty
Stoob
Valyn Hall
Cute Girl
Oliver Ryan Anderson
Cute Girl's Boyfriend
Curtis Taylor
Coach
Jesse Flanagan
Hurst
Dawn-Lyen Gardner
Coed
Laura Roth
Coed
Alexi Wasser
Female Student
Stacey Travis
Teacher
Wendy Haines
Grenadine Woman
Erik Walker
Punching Bully
Andre Marcus
Other Bully
Choice Skinner
Cop
Bob Jennings
Cop
Sam Sabbah
Scary Local
Lily Asinovsky
Girl Who Steps on Glass
Steve Buscemi
Broadway Bob D'Annunzio
Kristin Quick
Girl Student