Quvenzhané Wallis
Annie Bennett
Jamie Foxx
William "Will" Stacks
Rose Byrne
Grace Farell
Cameron Diaz
Miss Colleen Hannigan
Bobby Cannavale
Guy
David Zayas
Lou
Amanda Troya
Pepper
Zoe Colletti
Tessie
Eden Duncan-Smith
Isabella
Dorian Missick
Annie's "Dad"
Tracie Thoms
Annie's "Mom"
Mike Birbiglia
Social Services Inspector
Stephanie Kurtzuba
Mrs. Kovacevic
Peter Van Wagner
Harold Gray
Michael J. Fox
Himself
Raushanah Simmons
YaYa L'Occitane
DonnaMarie Recco
Woman on Street
Mila Kunis
Andrea Alvin
Ashton Kutcher
Simon Goodspeed
Rihanna
Moon Goddess
Patricia Clarkson
Focus Group Woman
Sia
Animal Care & Control Volunteer
Bobby Moynihan
Guy In Bar
Pat Kiernan
NY1 Reporter
Beth Rowe
Reporter
Jill Nocolini
Ms. Giannetti
Brad Bong
Pickle Stevens
Andrew Fleming
Cleve Sweetzer
Jessica Sherr
Mary Gillen
Scarlett Benchley
Fish Goddess
Ray Iannicelli
Waiter at Domani
Ty Jones
Stacks Mobile Reporter
Victor Cruz
Teacher
Taylor Richardson
Red Haired "Annie"
Derrick Baskin
Auditioning 'Dad'
Pernell Walker
Auditioning 'Mom'
Lytle Harper
Domani Reporter
J. Kaitlin Becker
Grace's Assistant
Ruby Rose Turner
Orphan #8 (uncredited)
Cynthia Basinet
Wealthy mother (uncredited)
Maesi Caes
Orphan #3 (uncredited)
Josh Elliott Pickel
(uncredited)
Lily Peterson
Tessie Photo Double
Patricia Pinto
Mom
Francesca Pinto
Friend of foster girls
Alan D. Purwin
Stacks' Pilot
Nicholas Pinto
Friend of foster girls
Bill Walters
Soup Kitchen Guest (uncredited)
Amyrh Harris
Classroom Kid
Gabriella Baldacchino
Classmate (uncredited)
Tate McRae
Orphan #17 (uncredited)
Degenerocity
Kid in Theater (uncredited)