Will Ferrell
Ron Burgundy
Christina Applegate
Veronica Corningstone
Paul Rudd
Brian Fantana
Steve Carell
Brick Tamland
David Koechner
Champ Kind
Fred Willard
Ed Harken
Chris Parnell
Garth Holliday
Kathryn Hahn
Helen
Fred Armisen
Tino
Seth Rogen
Eager Cameraman
Danny Trejo
Bartender
Scot Robinson
Waiter at Tino's
Ian Roberts
Stage Manager
Darcy Donavan
Hot Blonde
Renee Weldon
Petite Brunette
Jerry Minor
Tino's Bassist
Holmes Osborne
Director
Charles Walker
Security Guard
Shira Piven
Mother
Lili Rose McKay
Child
Thomas E. Mastrolia
Biker Guy
Jay Johnston
Eyewitness News Member
Peter A. Hulne
Man in Kitchen
Laura Kightlinger
Donna
Adam McKay
Custodian
Joseph T. Mastrolia
Custodian
Judd Apatow
News Station Employee
Debra McGuire
News Station Employee
Kent Shocknek
Network Reporter
Monique McIntyre
Yelling Woman
Bob Rummler
Bum
Charles Poynter
Announcer
Esmerelda McQuillan
Middle Class Mother
Angela Grillo
Elderly Woman
Lionel Allen
Wealthy Family Father
Trina D. Johnson
Wealthy Family Mother
Mary Alice G. Goodin
Wealthy Family Child
Yasmine Nickle
Wealthy Family Child
Fred H. Dresch
Doctor
Glen Hambly
Middle Class Dad
Stuart Gold
Nursing Room Resident
Bill Kurtis
Bill Lawson
Jack Black
Motorcyclist
Ben Stiller
Arturo Mendes
Luke Wilson
Frank Vitchard
Frank Gorgie
Frank the Bartender (uncredited)
Missi Pyle
Zoo Keeper (uncredited)
Tim Robbins
Public TV News Anchor (uncredited)
Vince Vaughn
Wes Mantooth (uncredited)
Jerry Stiller
Man in Bar (uncredited)
Holly Traister
Secretary (uncredited)
Matthew Vlahakis
Zoologist with Panda in Doug or Glen scene (uncredited)
Richard Yett
Reporter / Anchor (uncredited)