Jeffrey Wright
Thelonious 'Monk' Ellison
John Ortiz
Arthur
Erika Alexander
Coraline
Leslie Uggams
Agnes Ellison
Sterling K. Brown
Clifford Ellison
Skyler Wright
Brittany
John Ales
Leo
Patrick Fischler
Mandel
Carmen Cusack
Gilda
Joseph Marrella
Matthew Wilson
Stephen Burrell
Jordan Phillips
Issa Rae
Sintara Golden
Nicole Kempskie
Sintara's Moderator
Becki Dennis
Clinic Receptionist
Tracee Ellis Ross
Lisa Ellison
Myra Lucretia Taylor
Lorraine
Kate Avallone
Woman on Patio
Dustin Tucker
Phillip
Michael Jibrin
Jelani
Michele Proude
Bulger's Nurse
David De Beck
Dr. Bulger
Okieriete Onaodowan
Van Go Jenkins
Keith David
Willy the Wonker
Miriam Shor
Paula Baderman
Raymond Anthony Thomas
Maynard
Greta Quispe
Luz Borquez
J.C. MacKenzie
Carl Brunt
Elle Sciore
Layne
Adam Brody
Wiley Valdespino
Justin Andrew Phillips
Arthur's Intern
Neal Lerner
Wilson Harnet
Jenn Harris
Ailene Hoover
Bates Wilder
Jon Daniel Sigmarsen
Jason Armani Martinez
Nursing Home Orderly
Michael Cyril Creighton
John Bosco
Celeste Oliva
Dr. Tiefel
Megan Robinson
Kenya Dunston
Christopher Barrow
Burt
Alexander Pobutsky
Kenny
Tokunbo Joshua Olumide
Alvin
Chhoyang Cheshatsang
Wiley's Assistant
Michael Malvesti
Plainclothes Cop
Samantha Gordon
Gaby (uncredited)