Zachary Levi
Toby
David Cross
Ian
Jason Lee
Dave
Justin Long
Alvin (voice)
Matthew Gray Gubler
Simon (voice)
Jesse McCartney
Theodore (voice)
Amy Poehler
Eleanor (voice)
Anna Faris
Jeanette (voice)
Christina Applegate
Brittany (voice)
Wendie Malick
Dr. Rubin
Anjelah Johnson-Reyes
Julie
Kathryn Joosten
Aunt Jackie
Kevin G. Schmidt
Ryan
Chris Warren
Xander
Bridgit Mendler
Becca
Aimee Carrero
Emily
Alexandra Shipp
Valentina
Gregg Binkley
Emcee
Jake Zyrus
Charice Pempengco
Bernard White
Doctor
Adele Jacques
Nurse
Joy Osmanski
Airline Rep
Archie Hahn
Agent
Lanny Joon
Paramedic
Brando Eaton
Jeremy
Michael Bruno
Honor Society
Andrew Lee Schmidt
Honor Society
Alexander Noyes
Honor Society
Jason Rosen
Honor Society
Ali Mikles
Screaming Fan
Eric Bauza
Digger the NASCAR Gopher (voice)
Sean Astin
Meerkat Manor Narrator (voice)
Marty Dew
Chipmunk Dancer
Richy Jackson
Chipmunk Dancer
Mihran Kirakosian
Chipmunk Dancer
Janelle Ginestra
Chipette Dancer
Thomasina Gross
Chipette Dancer
Rachele Brooke Smith
Chipette Dancer
Ryan Conferido
Li'l Rosero Dancer
Hokuto 'Hok' Konishi
Li'l Rosero Dancer
Ryan Feng
Li'l Rosero Dancer
D-Trix
Li'l Rosero Dancer
Brian Hirano
Li'l Rosero Dancer
Steve Terada
Li'l Rosero Dancer
Victor Kim
Li'l Rosero Dancer
Brittany Anne Pirtle
Cheerleader (uncredited)
Ross Bagdasarian, Jr.
Alvin (singing voice) (uncredited)
Janice Karman
Theodore / The Chipettes (singing voice) (uncredited)
Steve Vining
Simon (singing voice) (uncredited)
Courtney Galiano
Eleanor - Performer (voice) (uncredited)
Gee Alexander
Simon Dance Double (uncredited)
Mark Alkofer
Football Referee (uncredited)
Tallie Brinson
Principal Dancer (uncredited)
Ericka Clevenger
Cheerleader (uncredited)
Sean Decker
Dodgeball Player (uncredited)
Sarah Fontenot
Cheerleader (uncredited)
Paul Gonzales
Charice Bassist (uncredited)
David Lautman
High School Student (uncredited)
Casper Smart
Dancer (uncredited)
Andrew 'Drew' Thompson
Stadium Announcer (uncredited)