Willem Dafoe
Cisco
Shanyn Leigh
Skye
Toni Redman
Man on phone (voice)
Pat Kiernan
News Anchor
Francis Kuipers
Teddy
Selena Mars
Skype Dancer
Justin Restivo
Suicide
Bojana Vasik
Woman with coat
Trung Nguyen
Delivery Boy
Triana Jackson
Cisco's Daughter
Dierdra McDowell
Cisco's Ex
Natasha Lyonne
Tina
Anita Pallenberg
Sky's Mother
Paul Hipp
Noah
José Solano
Drug Dealer
Judith Salazar
Friend of Dealer
Paz de la Huerta
Woman on Street
Frank Aquilino
Man Outside Bar
Maria Grazia Schirripa
Wailing Woman
Muriel Sprissler Dafoe
Cisco's Mother
Nicholas Deceolia
Man in Window
Tenzin Gyatso
Self (archive footage) (uncredited)
Al Gore
Self (archive footage) (uncredited)
Anthony Perullo
Contrition (uncredited)
Charlie Rose
Self (archive footage) (uncredited)
Tyler Stone
Man in Heels (uncredited)
Thomas Michael Sullivan
Priest (uncredited)
Nicola Tranquillino
Newscaster (uncredited)