Millie Bobby Brown
Enola Holmes
Henry Cavill
Sherlock Holmes
Sam Claflin
Mycroft Holmes
Helena Bonham Carter
Eudoria Holmes
Louis Partridge
Lord Tewkesbury
Adeel Akhtar
Lestrade
Fiona Shaw
Miss Harrison
Frances de la Tour
The Dowager
Burn Gorman
Linthorn
Susan Wokoma
Edith
Claire Rushbrook
Mrs. Lane
David Bamber
Sir Whimbrel
Hattie Morahan
Lady Tewkesbury
Gaby French
Seamstress
Paul Copley
Station Master
Ellie Haddington
Miss Gregory
Alex Kelly
Miss Gregory II
James Duke
Footman
Connor Catchpole
Gardener
Sarah Flind
Tea Shop Assistant
Dempsey Bovell
Fleet Street Hawker
Neil Bell
Constable
Sofia Stavrinou
Young Enola
Sophie Dixon
Toddler Enola
David Kirkbride
Agitator
Delroy Atkinson
Porter
Mary Roscoe
Grace Whitting
Anthony Aje
Newspaper Boy (House of Lords)
Anthony Rickman
Newspaper Boy (Fleet Street)
Philip Scott-Wallace
Newspaper Editor
Tuyen Do
Boarding School Teacher
Esther Coles
Miss Fox
Owen Atlas
Young Sherlock Holmes (uncredited)
Paul Parker
Police Inspector (uncredited)
Heather Pearse
Hawker (uncredited)
Jay Simpson
Conductor (uncredited)